生物学概念与途径课件下载_RAOLAB

生物学概念与途径课件下载

第一章孤独的天才

1A 一意孤行的伯乐

1B 达尔文的泛生假说

第二章遗传与染色体

2A 老兵不死：百年亿蝇为哪般？

第三章遗传信息的载体： DNA

第四章遗传密码

第五章细胞间相互作用：胚胎诱导

第六章发育的基因调控

第七章我与非我

第八章多样性：免疫球蛋白

第九章电传导

第十章化学传递

第十一章还原与整合

第十二章药物与生物

第十三章遗传筛选

第十四章分子生物学筛选

14A 美丽的荧光蛋白

第十五章生物化学分离纯化（未完待续）

15A神经生长因子

第一章

Mendel G (1866) Experiments in Plant Hybridization. Verhand- lungen des naturforschenden Vereines in Brünn, Bd. IV für das Jahr, Abhandlungen, 3-47(Experiments in Plant Hybridization in Genetics: readings from Scientific American pp. 8-17. W.H. Freeman and Company, San Francisco-USA)

第二章

Morgan TH (1910) Sex linked inheritance in Drosophila. Science 32:120-122.

Sturtevant AH (1913) The linear arrangement of six sex-linked factors in Drosophila as shown by mode of association. Journal of Experimental Zoology 14:39-45.

第三章

Griffith F (1928) The significance of pneumococcal types. Journal of Hygiene 27:113-159.

Avery OT, MacLeod CM and McCarty M (1944) Studies on the chemical nature of the substance inducing transformation of pneumococcal types. Journal of Experimental Medicine 79: 137-158.

第四章

Brenner S (1957) On the impossibility of all overlapping triplet codes in information transfer from nucleic acid to proteins. Proceedings of the National Academy of Sciences USA 43:687-694.

Lengyel P, Speyer JF, Ochoa S (1961) Synthetic polynucleotides and the amino acid code. Proceedings of the National Academy of Sciences USA 47:1936-1942.

第五章

Spemann H and Mangold H (1924) Über Induktion von Embryonalanlagen durch, Implantation artfremder Organisatoren. Archive für Mikroskopische Anatomie Entwicklungsmechanik 100:599-638. (translated as Spemann H and Mangold H (2001). Induction of embryonic primordia by implantation of organizers from a different species. International Journal of Developmental Biology 45:13-38).

Nieuwkoop PD (1969) The formation of the mesoderm in urodelean amphibians. I. Induction by the endoderm. Wilhelm Roux’ Archive of Developmental Biology 162:341-373.

第六章

Lewis EB (1978) A gene complex controlling segmentation in Drosophila. Nature 276:565–570.

Nüsslein-Volhard C and Wieschaus E (1980) Mutations affecting segment number and polarity in Drosophila. Nature 287:795–801.

第七章

Behring E and Kitasato S (1890) Über das Zustandekommen der Diphtherie-Immunität und der Tetanus-Immunität bei Thieren. Deutsche medizinische Wochenschrift 16:1113-1114 (The mechanism of immunity in animals to diphtheria and tetanus).

Landsteiner K (1901) Über Agglutinationserscheinungen normalen menschlichen Blutes. Wiener Klinische Wochenschrift 14:1132-1134. (On the agglutination of normal human blood).

第八章

Burnet F (1957) A modification of Jerne’s theory of antibody production using the concept of clonal selection. Australian Journal of Science 20:67-69.

Hozumi N and Tonegawa S (1976) Evidence for somatic rearrangement of immunoglobulin genes coding for variable and constant regions. Proceedings of the National Academy of Sciences USA 73:3628-3632.

第九章

Curtis HJ and Cole KS (1940) Membrane action potentials from the squid giant axon. Journal of Cellular and Comparative Physiology 15:147-157.

Hodgkin AL and Huxley AF (1952a) Currents carried by sodium and potassium ions through the membrane of the giant axon of Loligo. Journal of Physiology 116:449–472.

第十章

Elliot TR (1905) On the action of adrenalin. Journal of Physiology 32:401-467.

Dale HH, Feldberg W and Vogt M (1936) Release of acetylcholine at voluntary motor nerve endings. Journal of Physiology 86: 353-380.

第十一章

Nathans J, Piantanida TP, Eddy RL, Shows TB and Hogness DS (1986) Molecular genetics of inherited variation in human color vision. Science 232:203-210.

Hubel DH and Wiesel TN (1962) Receptive fields, binocular interaction and functional architecture in the cat’s visual cortex. Journal of Physiology 160:106-154.

第十二章

Fleming A (1929) On the antibacterial action of cultures of a penicillium, with special reference to their use in the isolation of B. influenzae. British Journal of Experimental Pathology 10:226-236.

Liu, J, Farmer JD Jr, Lane WS, Friedman J, Weissman I, Schreiber SL (1991) Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes. Cell 66:807-15

第十三章

Konopka RJ and Benzer S (1971) Clock mutants of Drosophila melanogaster. Proceedings of the National Academy of Sciences USA 68:2112-2116.

Vitaterna MH, King DP, Chang A-M, Kornhauser JM, Lowrey PL, McDonald JD, Dove WF, Pinto LH, Turek FW and Takahashi JS (1994) Mutagenesis and mapping of a mouse gene, Clock, essential for circadian behavior. Science 264:719-725.

第十四章

Schatz DG, Oettinger MA and Baltimore D (1989). The V(D)J recombination activating gene, RAG1. Cell 59:1035-1048.

Jinek M, Chylinski K, Fonfara I, Hauer M, Doudna JA and Charpentier E (2012). A programmable dual-RNA-guided DNA endoclease in adaptive bacterial immunity. Science 337:816-821.

第十五章

Vale RD, Reese TS and Sheetz MP (1985). Identification of a novel force-generating protein, kinesin, involved microtubule-based motility. Cell 42:39-50.

Prusiner SB (1982). Novel proteinaceous infectious particles cause scrapie. Science,216:136-144.

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